The Nemes Research Laboratory (NRG) has pioneered ultrasensitive proteomics for cell and developmental biology and neuroscience and has discovered molecules capable of altering normal cell fate decisions (see group website: http://blog.umd.edu/nemes/). The NRG is hereby seeking a talented and motivated postdoctoral researcher with existing experience in bottom-up proteomic workflows of sample preparation, nano-flow liquid chromatography, orbitrap mass spectrometry, multiplexing quantification (e.g., TMT, iTRAQ), and bioinformatics (e.g., SEQUEST, MaxQuant, etc.). The applicant will work with and help lead an interdisciplinary team of scientists consisting of faculty, postdocs, and graduate students to establish (ultra)sensitive quantitative workflows to enable the interrogation of molecular mechanisms that are critical for cell differentiation and embryonic development but have been unavailable for investigation due to limitations in analytical sensitivity. The ideal candidate is already experienced in routinely operating and maintaining the Ultimate 3000 RSLCnano Orbitrap Fusion Lumos system.
Experience in tools of molecular biology is a bonus. Prior experience in working with the AB Sciex CESI capillary electrophoresis instrument is a bonus but is not required. Experience working with custom-built instrumentation or custom-building instrumentation is welcome but is not required.
The proactive and self-motivated candidate will have the opportunity to learn new skills in ultrasensitive proteomics, mass spectrometry instrumentation, and cell/developmental biology. The NRG owns a comprehensive suite of mass spectrometers, LC and CE systems, bioinformatics software packages, a live animal colony, and all the infrastructure to provide a productive experience for the motivated post-doctoral scientist. The position is open until filled.
University Of Maryland