Postdoc Research Associate

Position Title:

Postdoc Research Associate

Appointment Type:

Post Doc/Trainee

Job Description:

Summary of Duties and Responsibilities:

An NIH funded postdoctoral position is available in the MacIntosh lab to study the role of lysosomal proteins in endocytosis and lipid transport in Drosophila. We are also interested in the connection between these processes and lysosomal disorders, including Parkinson's disease. The laboratory uses a multidisciplinary approach, including microscopy, metabolomics, and transcriptomics analyses to uncover the metabolic pathways that control acidification of the endocytic pathway, the role of endocytic processes in interorgan lipid transport, and homeostasis. For recent publications supporting this project and the open questions that we want to address, please see Chaudhry et al. 2022. Autophagy 18 (10), 2443-2458; Handy et al. 2024. Autophagy 20 (2), 437-440. In addition, there will be opportunities for gaining mentorship experience via helping to train junior investigators in the group and for developing projects contributing to their own related areas of interest to start an independent career.

We are seeking a motivated individual with a Ph.D. in biochemistry, cell and molecular biology, or related areas. Experience in Drosophila molecular genetics is preferred. Candidates should have a strong interest and background in one or more of the following: lipid biology, molecular biology, imaging, bioinformatics and systems biology, cell biology, and/or animal models of disease. The successful applicant will have excellent organizational and communication skills, a commitment to detail, the ability to work both independently and as part of a larger team, and a demonstrated capacity to perform creative and original research.

To guarantee full consideration, applications must be received by 7/15/2024

Required Minimum Qualifications:

PhD

Preferred Qualifications:

• Experience in Drosophila dissections and molecular genetics strongly preferred.

• Experience analyzing metabolomics and/or transcriptomics datasets.

• Experience with expression (E. coli, yeast, and insect cells) and purification of proteins.

• Experience with confocal microscopy.

• Familiarity with lipid metabolism.

Proposed Start Date:

August 12, 2024

Proposed End Date or Length of Term:

August 11, 2026

Number of Months Employed Per Year:

12 Month Work Period

Time Type:

Full time

Application Instructions:

To apply for this position, please click on "Apply" and complete the Employment Application. Please be prepared to enter or attach the following:

1. Resume/Curriculum Vitae

2. Letter of Application/Cover Letter

If you have questions regarding this application process, please email employment@iastate.edu or call 515-294-4800 or Toll Free: 1-877-477-7485.

Why Choose ISU?

Iowa State Postdocs enjoy comprehensive health and work-life benefits, including medical and dental; as well as:

• Retirement benefits including defined benefit and defined contribution plans

• Generous vacation, holiday, and sick time and leave plans

• Onsite childcare (Ames, Iowa)

• Flexible Spending Accounts

• Various voluntary benefits and discounts

• Employee Assistance Program

• Wellbeing Program

Original Posting Date:

July 1, 2024

Posting Close Date:

July 15, 2024

Job Requisition Number:

R14968