Post Doctoral Scientist - Research Cardiovascular- Dr. Zhao's Lab

Nationwide Children's Hospital Columbus , OH 43216

Posted 2 months ago

Overview

Post Doctoral Scientist - Research Cardiovascular- Dr. Zhao's lab

A postdoctoral scientist position is immediately available in Dr. Mingtao Zhao's laboratory in the Center for Cardiovascular Research at the Nationwide Children's Hospital and The Ohio State University in Columbus, Ohio. The Zhao lab is using patient-derived induced pluripotent stem cells (iPSCs), CRISPR/Cas9 genome editing, and single-cell genomics to study the molecular and genetic mechanisms of cardiovascular development and congenital heart disease (PNAS 2017, PMID: 29203658; Circ Res 2017, PMID: 29030344; Stem Cells 2020, PMID: 32232889, Front Cell Dev Biol 2021, PMID: 33585486). The goal of the Zhao lab is to elucidate the cause-consequence relationship of a given genetic variant in regulatory elements (such as enhancers) in the contribution of cardiovascular disease using patient-specific iPSCs that retain all genetic information of the affected patients. The Zhao lab is currently funded by NIH/NHLBI, Additional Ventures, AHA and Abigail Wexner Research Institute at Nationwide Children's Hospital. This is a great opportunity for young investigators who aim to establish an independent academic career in the next few years. Successful candidates should have a PhD/MD or equivalent degree (< 3 years after graduation) and should have solid expertise in cardiac physiology, cardiovascular development, or organoid biology. candidates who have additional expertise in bioinformatics or crispr/cas9 genome editing or tissue engineering would be preferred.the center for cardiovascular research currently has a nih-funded t32 postdoctoral program to provide interdisciplinary, translational, and state-of-the-art research training in congenital and acquired heart disease, partnered with the ohio state university college of medicine. the abigail wexner research institute is one of the largest pediatric research centers and consistently ranked among the top 10 for nih funding among free-standing children's hospitals in the united states. in addition, nationwide children's hospital has been consistently ranked on the us news & world report's "america's best children's hospitals honor roll".

potential candidates should send their cv (with publication list) and cover letter describing future research vision to

mingtao zhao, phd

principal investigator

center for cardiovascular research

nationwide children's hospital

assistant professor

departments of pediatrics

the ohio state university college of medicine

email: mingtao.zhao@nationwidechildrens.org

schedule: (full time, benefits eligible)

location:

research i i i700 children's drcolumbus, ohio 43205

why nationwide children's hospital?

the moment you walk through our doors, you can feel it. when you meet one of our patient families, you believe it. and when you talk with anyone who works here, you want to be part of it, too. welcome to nationwide children's hospital, where passion meets purpose.

here, everyone matters. we're 13,000 strong. and it takes every single one of us to improve the lives of the kids we care for, and the kids from around the world we'll never even meet. kids who are living healthier, fuller lives because of the knowledge we share. we know it takes a collaborative culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. anywhere.

ask anyone with a nationwide children's badge what they do for a living. they'll tell you it's more than a job. it's a calling. it's a chance to use and grow your talent to make an impact that truly matters. because here, we exist simply to help children everywhere.

nationwide children's hospital. a place to be proud

responsibilities

  • performing cardiac differentiation and organoid induction
  • design and conduct scientific experiments to obtain data
  • write and publish scientific manuscripts
  • contribute to grant submissions for external funding
  • obtain postdoctoral fellowship and career development award from the aha and/or nih

qualifications

knowledge, skills and abilities required:

education:

  • phd. or equivalent doctorate in cell/molecular/developmental biology, cardiovascular physiology, genomics or related field

experience:

  • desire to pursue a career in biomedical research
  • knowledge of the research process.
  • necessary technical skills in the appropriate area of research.
  • ability to do technical writing and good communication skills.

eoe/m/f/disability/vet. 3="" years="" after="" graduation)="" and="" should="" have="" solid="" expertise="" in="" cardiac="" physiology,="" cardiovascular="" development,="" or="" organoid="" biology.="" candidates="" who="" have="" additional="" expertise="" in="" bioinformatics="" or="" crispr/cas9="" genome="" editing="" or="" tissue="" engineering="" would="" be="" preferred.the="" center="" for="" cardiovascular="" research="" currently="" has="" a="" nih-funded="" t32="" postdoctoral="" program="" to="" provide="" interdisciplinary,="" translational,="" and="" state-of-the-art="" research="" training="" in="" congenital="" and="" acquired="" heart="" disease,="" partnered="" with="" the="" ohio="" state="" university="" college="" of="" medicine.="" the="" abigail="" wexner="" research="" institute="" is="" one="" of="" the="" largest="" pediatric="" research="" centers="" and="" consistently="" ranked="" among="" the="" top="" 10="" for="" nih="" funding="" among="" free-standing="" children's="" hospitals="" in="" the="" united="" states.="" in="" addition,="" nationwide="" children's="" hospital="" has="" been="" consistently="" ranked="" on="" the="" us="" news="" &="" world="" report's="" "america's="" best="" children's="" hospitals="" honor="" roll".="" potential="" candidates="" should="" send="" their="" cv="" (with="" publication="" list)="" and="" cover="" letter="" describing="" future="" research="" vision="" to="" mingtao="" zhao,="" phd="" principal="" investigator="" center="" for="" cardiovascular="" research="" nationwide="" children's="" hospital="" assistant="" professor="" departments="" of="" pediatrics="" the="" ohio="" state="" university="" college="" of="" medicine="" email:="" mingtao.zhao@nationwidechildrens.org="" schedule:="" (full="" time,="" benefits="" eligible)="" location:="" research="" i="" i="" i700="" children's="" drcolumbus,="" ohio="" 43205="" why="" nationwide="" children's="" hospital?="" the="" moment="" you="" walk="" through="" our="" doors,="" you="" can="" feel="" it.="" when="" you="" meet="" one="" of="" our="" patient="" families,="" you="" believe="" it.="" and="" when="" you="" talk="" with="" anyone="" who="" works="" here,="" you="" want="" to="" be="" part="" of="" it,="" too.="" welcome="" to="" nationwide="" children's="" hospital,="" where="" passion="" meets="" purpose.="" here,="" everyone="" matters.="" we're="" 13,000="" strong.="" and="" it="" takes="" every="" single="" one="" of="" us="" to="" improve="" the="" lives="" of="" the="" kids="" we="" care="" for,="" and="" the="" kids="" from="" around="" the="" world="" we'll="" never="" even="" meet.="" kids="" who="" are="" living="" healthier,="" fuller="" lives="" because="" of="" the="" knowledge="" we="" share.="" we="" know="" it="" takes="" a="" collaborative="" culture="" to="" deliver="" on="" our="" promise="" to="" provide="" the="" very="" best,="" innovative="" care="" and="" to="" foster="" new="" discoveries,="" made="" possible="" by="" the="" most="" groundbreaking="" research.="" anywhere.="" ask="" anyone="" with="" a="" nationwide="" children's="" badge="" what="" they="" do="" for="" a="" living.="" they'll="" tell="" you="" it's="" more="" than="" a="" job.="" it's="" a="" calling.="" it's="" a="" chance="" to="" use="" and="" grow="" your="" talent="" to="" make="" an="" impact="" that="" truly="" matters.="" because="" here,="" we="" exist="" simply="" to="" help="" children="" everywhere.="" nationwide="" children's="" hospital.="" a="" place="" to="" be="" proud="" responsibilities="" *="" performing="" cardiac="" differentiation="" and="" organoid="" induction="" *="" design="" and="" conduct="" scientific="" experiments="" to="" obtain="" data="" *="" write="" and="" publish="" scientific="" manuscripts="" *="" contribute="" to="" grant="" submissions="" for="" external="" funding="" *="" obtain="" postdoctoral="" fellowship="" and="" career="" development="" award="" from="" the="" aha="" and/or="" nih="" qualifications="" knowledge,="" skills="" and="" abilities="" required:="" education:="" *="" phd.="" or="" equivalent="" doctorate="" in="" cell/molecular/developmental="" biology,="" cardiovascular="" physiology,="" genomics="" or="" related="" field="" experience:="" *="" desire="" to="" pursue="" a="" career="" in="" biomedical="" research="" *="" knowledge="" of="" the="" research="" process.="" *="" necessary="" technical="" skills="" in="" the="" appropriate="" area="" of="" research.="" *="" ability="" to="" do="" technical="" writing="" and="" good="" communication="" skills.="">

potential candidates should send their cv (with publication list) and cover letter describing future research vision to

mingtao zhao, phd

principal investigator

center for cardiovascular research

nationwide children's hospital

assistant professor

departments of pediatrics

the ohio state university college of medicine

email: mingtao.zhao@nationwidechildrens.org

schedule: (full time, benefits eligible)

location:

research i i i700 children's drcolumbus, ohio 43205

why nationwide children's hospital?

the moment you walk through our doors, you can feel it. when you meet one of our patient families, you believe it. and when you talk with anyone who works here, you want to be part of it, too. welcome to nationwide children's hospital, where passion meets purpose.

here, everyone matters. we're 13,000 strong. and it takes every single one of us to improve the lives of the kids we care for, and the kids from around the world we'll never even meet. kids who are living healthier, fuller lives because of the knowledge we share. we know it takes a collaborative culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. anywhere.

ask anyone with a nationwide children's badge what they do for a living. they'll tell you it's more than a job. it's a calling. it's a chance to use and grow your talent to make an impact that truly matters. because here, we exist simply to help children everywhere.

nationwide children's hospital. a place to be proud

responsibilities

  • performing cardiac differentiation and organoid induction
  • design and conduct scientific experiments to obtain data
  • write and publish scientific manuscripts
  • contribute to grant submissions for external funding
  • obtain postdoctoral fellowship and career development award from the aha and/or nih

qualifications

knowledge, skills and abilities required:

education:

  • phd. or equivalent doctorate in cell/molecular/developmental biology, cardiovascular physiology, genomics or related field

experience:

  • desire to pursue a career in biomedical research
  • knowledge of the research process.
  • necessary technical skills in the appropriate area of research.
  • ability to do technical writing and good communication skills.

eoe/m/f/disability/vet.>

icon no score

See how you match
to the job

Find your dream job anywhere
with the LiveCareer app.
Mobile App Icon
Download the
LiveCareer app and find
your dream job anywhere
App Store Icon Google Play Icon
lc_ad

Boost your job search productivity with our
free Chrome Extension!

lc_apply_tool GET EXTENSION

Similar Jobs

Want to see jobs matched to your resume? Upload One Now! Remove
Research Assistant Center For Mathematical Medicine Dr Das Lab

Nationwide Children's Hospital

Posted 2 months ago

VIEW JOBS 9/15/2021 12:00:00 AM 2021-12-14T00:00 Overview Research Assistant- Center for Mathematical Medicine- Dr. Das Lab A position for a research assistant is available immediately in the Das Lab (http://www.nationwidechildrens.org/jayajit-das) at the Battelle Center for Mathematical Medicine at The Research Institute at Nationwide Children's Hospital and the Ohio State University located at Columbus, Ohio, USA. The position is funded by the NIH and we are seeking outstanding candidates who are interested in applying computational/mathematical methods for analyzing protein sequence and single cell for Natural Killer cells responding to viral infections. The assistant is expected to work closely with our experimental collaborators and analyze KIR, HLA sequence data from donors, and replicon experiments and develop data-driven and mechanistic mathematical models. The candidate is required to have expertise in one of the following techniques: analysis of protein sequence data, numerical solution of ordinary differential equations, and machine learning tools. Some experience with modeling biophysical systems will be considered a plus. The candidate is required to know to code in Python/R/C/C++. No previous background in immunology is required, however, the fellow is expected to learn backgrounds pertaining to projects of interest and contribute to discussions with our experimental collaborators. The experience gained at this position is expected to train the assistnat to seek career opportunities in academia or industry in the areas of data science/computational biology. Applicants with a MS degree in Bioinformatics/Computer Science/Chemistry/Biophysics/Computer Science are encouraged to apply. Das lab has access to a state-of-the-art computer cluster over 800 INTEL processors. Resources at the Ohio State University campus and Ohio Supercomputer Center are also available. The position will be initially for one year and can be potentially renewed. Interested candidates should email a brief cover letter stating your interest in our lab, a short CV and names and contact information of three referees to jayajit@gmail.com or das.70@osu.edu . Schedule: (Full time, Benefits Eligible) Location: Research II700 Children's DrColumbus, Ohio 43205 Why Nationwide Children's Hospital? The moment you walk through our doors, you can feel it. When you meet one of our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it, too. Welcome to Nationwide Children's Hospital, where Passion Meets Purpose. Here, Everyone Matters. We're 13,000 strong. And it takes every single one of us to improve the lives of the kids we care for, and the kids from around the world we'll never even meet. Kids who are living healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere. Ask anyone with a Nationwide Children's badge what they do for a living. They'll tell you it's More Than a Job. It's a calling. It's a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere. Nationwide Children's Hospital. A Place to Be Proud Responsibilities * Performs research experiments independently or semi-independently in accordance with protocols approved by the principal investigator. Such experiments may involve the use of laboratory animals or human subjects any may require evening and/or weekend duties. * Prepares and tests substrate, conducts assays, and prepares tissue cultures for use in research studies, as applicable. Collects blood, urine, and other samples as needed. Such activities may be performed independently and may require evening and weekend hours. * Ensures accuracy of laboratory analytical procedures as required by specific research projects. * Collects and controls experimental data and patient information; and maintains accurate daily logs of experiments including methods, results, and conclusions. * Interprets the results of data analyses with input from the principal investigator. * Assists the principal investigator in the preparation of scientific publications and grant proposals. * Make recommendations about refinement and/or replacement of laboratory analytical procedures. Implements such refinements or new procedures with input from the principal investigator. * Orders supplies needed to conduct research; maintains inventory of equipment and supplies; and assures that research equipment is in good working order. * Collaborates in the preparation of research budgets, and monitors expenditure of funds to assure that studies are conducted within budgetary constraints. * Instructs other laboratory workers and students in standard methods, practices, procedures, and equipment operations. * Maintains a clean working area and performs general laboratory maintenance. Adheres to proper safety techniques and procedures. * Performs miscellaneous related duties. Qualifications KNOWLEDGE, SKILLS AND ABILITIES REQUIRED: Education: * Bachelor of Science degree with two to three years of laboratory research experience OR certification and experience may be considered in lieu of formal education. Experience: * Laboratory experience preferred * Coursework in anatomy, physiology, statistics, and relevant research methods. Minimum Physical Requirement: * Kneeling / reaching (Frequently) * Finger dexterity (Frequently) * Talking / hearing / seeing (Frequently) * Lifting / carrying weight 0-20 pounds for 1-5 minutes (Occasionally) EOE/M/F/Disability/Vet. Nationwide Children's Hospital Columbus OH

Post Doctoral Scientist - Research Cardiovascular- Dr. Zhao's Lab

Nationwide Children's Hospital