NGS Data Analysis Optimization - Intern

Metagenomi is a gene editing company committed to developing potentially curative therapeutics by leveraging a proprietary toolbox of next-generation gene editing systems to accurately edit DNA where current technologies cannot. Our metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. We adapt and forge these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific and have a decreased risk of immune response. These systems fuel our pipeline of novel medicines and can be leveraged by partners. Our goal is to revolutionize gene editing for the benefit of patients around the world.

Whether it's the biological diversity of our gene editing systems or the people that help discover them, Metagenomi celebrates the diversity of life. This is achieved through a compassionate culture that acknowledges the dimensions of our diversity. We know that when people feel a sense of inclusion and belonging in the workplace, they have a safe space to bring creativity and innovation to everything they do. We are intentional about building and maintaining a culture where people are valued and respected, there is equity in opportunities, and our respective opinions and differences matter.

Application Guidelines:

• Resume: Highlight relevant coursework, laboratory experience, and relevant technical skills (specific molecular biology techniques, software proficiency).

• Cover Letter:

• Briefly outline why you are interested in this internship specifically.

• Connect 2-3 of your strongest skills directly to the responsibilities outlined in the job posting.

Join us and make a direct impact on the future of therapeutic tools!

Metagenomi Bioinformatics Summer Intern We're looking for a talented Bioinformatics Summer Intern passionate about developing solutions to next-generation sequencing (NGS) data analysis problems in the field of gene editing. You'll work closely with our team to enhance tools and methods that directly impact a wide range of preclinical programs and have the potential to influence Discovery research.

The Opportunity:

• Optimize current NGS data processing and analysis pipelines to help advance our unique gene editing systems.

• Explore the development of an AI tool or statistical method to accelerate our guide selection process.

• Collaborate with scientists across Preclinical and Discovery teams to drive meaningful advancements.

How You'll Contribute:

• Optimize existing NGS workflows and identify areas for algorithm improvements.

• Implement and test new bioinformatics tools or refine existing ones for enhanced data analysis.

• Prototype an AI solution or statistical method using our large in house NGS datasets.

Must-Haves:

• Education: Actively pursuing a degree in Bioinformatics, Computational Biology, Biostatistics or a related field.

• Experience:

• Strong understanding of NGS data formats and analysis concepts.

• Proven scripting and data analysis skills (Python, R).

• Familiarity with biological databases (gnomAD, Ensembl) and analysis tools (vep).

• Experience with machine learning techniques.

• Knowledge of cloud computing platforms (AWS).

We strongly encourage applications from individuals of all backgrounds. Diversity drives our innovation!

Program Details:

Duration: Eight-week internship Dates: June 24, 2024 - August 16, 2024 Location: Onsite in Emeryville, California Hours: 9 am - 5 pm PST

California Pay Transparency Disclosure:

Under the Federal Labor Standards Act, this position is classified non-exempt. The hourly rate range for 2024 Summer Internships is $25.00 to $35.00 per hour, not to exceed 40 hours per week. Compensation for this internship will be determined at the Company's sole discretion and may vary based on depth of relevant experience and education.

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What makes Metagenomi a unique place to work?

• We are passionate about developing technologies derived from microbial-rich ecosystems that have the power to enable therapeutic development and the potential to cure devastating diseases.

• We have cultivated an amazing culture that values teamwork, curiosity, scientific rigor, and fun. We have a strong commitment to work/life balance, host a weekly employee happy hour and events, provide catered lunches and endless snacks, and more!

• We offer competitive compensation, including a market-benchmarked salary, annual target bonus potential, equity, comprehensive benefits plan, 401(k) with company matching, retirement safe harbor plan, and other perks.

At Metagenomi, we know that our people drive our success. We are an equal opportunity employer and believe in and value diversity and inclusion. Metagenomi provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term careers. Metagenomi does not discriminate on the basis of race, color, religion, sexual orientation, gender, age, physical or mental disability, or any other status protected under federal, state, or local law.

Applicants/Employees have rights under various State and Federal Employment Laws, including without limitation:

• Family & Medical Leave Act

• Equal Employment Opportunity Commission

• Employee Polygraph Protection Act

• California Family Rights Act

• California Fair Employment and Housing Act

Notice to agencies: Our in-house Talent Acquisition Team manages all employment opportunities at Metagenomi. Agencies and independent recruiters must be approved as a vendor by Metagenomi's Talent Acquisition team. To protect the interests of all parties, Metagenomi will not accept unsolicited resumes, profiles, or biographies. Any unsolicited resumes sent to Metagenomi will be considered referrals and the property of Metagenomi.