Investigator, Functional Genomics

Glaxosmithkline Collegeville , PA 19426

Posted 3 weeks ago

Site Name: USA - Pennsylvania - Upper Providence

Posted Date: May 31 2020

We are seeking a highly motivated scientist with established track records in genome editing technologies to join our Functional Genomics Department in Upper Providence. The group will support identification of novel targets, advance technologies in genome editing in addition to stem cell biology, and publish findings in peer reviewed journals. The scientists will have the opportunity to work on targets in multiple therapeutic areas including Oncology and Immunology. This is a laboratory position in which the individual will also be part of an extensive internal and external network to identify new opportunities in the development of disease-relevant models for use in drug discovery and target identification. The selected candidate will be expected to support the development of others and assist in setting strategic objectives in the genome editing and stem cell biology space.

Key Responsibilities:

  • Support target identification and drug discovery programs by applying specialist knowledge and expertise in genome editing and stem cell biology in the design and implementation of program team objectives and discovery tactics.

  • Provide scientific and technical guidance in the development of disease relevant models utilizing genome editing strategies in the target identification and drug discovery process, including genomic screening

  • In conjunction with internal and external partners (including biotech and academic labs), evaluate and implement new technologies in stem cells and genome editing.

  • Demonstrate strong scientific leadership as well as excellent written and oral communication.

  • Ensure compliance with all GSK R&D data integrity practices, ethics codes, work practice training and standards.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • A Ph.D in a life sciences discipline with 0 years of experience or a masters degree in a life sciences discipline with 3 years of relevant experience

  • Strong track-record in genome editing technologies, especially CRISPR/Cas9 related.

  • Experience with culture and differentiation of induced pluripotent stem cells

Preferred Qualifications:

If you have the following experience, it would be a plus:

  • Transient techniques in genome editing technology

  • Transcription regulation of genes using CRISPR/Cas9

  • Molecular genomics, molecular design for developing genome editing tools

  • Practical knowledge of cell biology and molecular analysis of cellular function, with familiarity with one or more of the following:

  • Cellular phenotypic assays

  • Predictive disease-relevant cell/tissue culture models such as primary cells, stem cells, co-cultures, and 3-dimensional culture

  • Induced pluripotent stem cells and differentiation

Why GSK?

Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:

  • Agile and distributed decision-making - using evidence and applying judgement to balance pace, rigour and risk, governance and control, managing ambiguity and paradox.

  • Managing individual performance.

  • Creating a performance culture and driving results, prioritisation, execution, delivering performance.

  • Setting strategic direction and leading on-going organisational transformation.

  • Building a resilient organisation.

  • Building strong relationships and collaboration in service of common goals, engaging the organisation and building trusted external networks for mutual benefit.

  • Managing P&L and capital allocation.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.


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Investigator, Functional Genomics

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