In Vivo Resources Associate

Agios Pharmaceuticals Cambridge , MA 02138

Posted 4 months ago

In Vivo Resources (IVR) Associate, Pharmacology

Agios (agios.com) is a biopharmaceutical company committed to applying our scientific leadership in cellular metabolism to transform the lives of patients with cancer and rare genetic diseases. We are growing rapidly with an active research and discovery pipeline across both therapeutic areas. Agios has two approved oncology precision medicines and multiple first-in-class investigational therapies in clinical and/or preclinical development.

Agios Pharmaceuticals has an opportunity for a skilled, professional, in vivo technician to join our Pharmacology team in conducting in vivo studies within our rodent-based drug discovery/exploratory research program. Responsibilities include in vivo technical execution, research interactions, data collection, animal husbandry, and facility maintenance/monitoring. Candidates must be able to work both independently and within a decentralized team environment while possessing strong communication, organization, motivation and multi-tasking skills. This position includes weekend, off-hour and holiday responsibilities.

Responsibilities

  • 1o Conduct daily animal health monitoring, husbandry and receipt of animal shipments. Identify and respond to clinical conditions.

  • 2o Organize and perform in vivo studies to include compound formulation, body weights, tumor calipering, body condition scoring, compound administration (PO, SC, IP, IV), blood collection, clinical observations, anesthesia/analgesia, euthanasia, necropsy, tissue collection/preparation and data collection.

  • Perform facility maintenance including supply procurement/stocking, sanitization/sterilization of equipment and environment, waste management, and monitoring environmental parameters

  • Review SOPs & IACUC documents

  • Confirmation and adherence of program compliance with IACUC and EHS regulations/standards. Maintain personal compliance with Agios institutional expectations (training, timecards, etc.).

  • Continuously pursue and support learning/professional development opportunities for self and team

Qualifications

Education/Knowledge

  • English comprehension (reading, writing, verbal)

  • Bachelor's degree with 1-3 years laboratory animal experience

  • AALAS ALAT or LAT certification preferred; ALAT required within 1 year of start.

  • Recognition and response to normal/abnormal animal conditions & behaviors

  • Experience with immunocompromised, competent and genetically engineered rodent models

  • Working knowledge of institutional, local and federal animal welfare regulations

  • Microsoft Office, Outlook and data base knowledge.

Abilities

  • Skilled in rodent care (husbandry, clinical assessment and treatment)

  • Familiarity with in vivo techniques (compound administration, blood collection, necropsy/tissue collection) and vivarium operations (stock & waste management, sanitation)

  • Strong communication skills (verbal, written)

  • Team oriented and interactive

  • Ability to work within a fast-paced, continually evolving in vivo research environment

  • Draft and review documents such as SOPs, signage and record logs

  • Lift, push, pull up to 50lb, stand for extended periods of time and perform repetitive motions

  • Availability during off-hours, weekends, holidays and during inclement weather

Competencies

  • Drive & Deliver

  • Strong commitment to consistent, high-caliber animal care and technical execution

  • Strong organizational, attention-to-detail, multi-tasking and follow-thorough skills

  • Build & Transform

  • Supportive of transitional operations and schedule changes

  • Committed to professional development and continuous learning; support avenues for peer/team development and performance

  • Connect & Relate

  • Strong interpersonal skills (transparency, professionalism, communication)

  • Team oriented, supportive and interactive

  • Lead From Every Chair

  • Independent self-starter requiring no/minimal daily oversight

  • Strong sense of personal accountability, reliability and integrity

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In Vivo Resources Associate

Agios Pharmaceuticals