Federation Bio South San Francisco , CA 94080

Posted 1 week ago

Our bodies play host to a spectacular constellation of microorganisms that impact virtually every aspect of human health. An emerging scientific understanding of the human microbiome is transforming our relationship with microbes elevating them from menace to medicine as our understanding of their profound role in human physiology has come into focus.

At Federation Bio, we design, discover, and develop robust communities of microbes that improve the human condition. Our approach combines a broad array of beneficial microbes into highly diverse consortia optimized for indication-specific potency. These metabolically comprehensive communities are designed to stably engraft in patients to sustain a durable therapeutic effect. In some instances, we augment our consortia with specialized human microbiome strains that have been trained through genetic engineering to harness the power of the human immune system to reverse disease.

Description of Role

We are seeking a highly qualified Immune-oncologist. The ideal candidate will have strong background in T cell biology of cancer, cancer immunotherapy, and functional interactions between the host-associated microbiota and immune system. The candidate needs to be flexible, excited to meet the dynamic needs of a start-up company, proactive and positive. This person should also have a desire to contribute to a vibrant and dynamic culture. He or she will have the interpersonal skills required to communicate and collaborate effectively with a first-rate scientific team as well as manage a small vivarium team. You will play a critical role in the development of novel microbiome therapeutics to support the development of exciting new therapies across a variety of diseases.

The Ideal candidate will have:

  • Solid understanding of the interplay between the microbiome and immune effector cell responses in the gut or skin, especially in the context of oncology as evidenced by peer-reviewed journal publications
  • Deep immune-oncology expertise in an industry setting, which contributed to the discovery and advancement of molecules into clinical develop
  • Expertise in antigen-presentation and innate immune and T cell regulation of cancer immunotherapy
  • Knowledge of tumor-associated and neoantigens across a variety of cancers, neo-antigen discovery and identification, and T cell receptor engineering
  • Proven track record of leading scientific discovery and development programs from lead discovery through IND enabling studies
  • Management experience is desired
  • PhD in Immunology, Cancer biology or other relevant fields of study
  • 4+ years experience in a biotech/industry setting
  • Ability to work as an independent researcher in the lab but also lead discovery teams
  • Critical thinking skills and clear communication are a necessity to provide strategic experimental guidance and contribute to data interpretation with the team
  • A strong ability to flex with the changing needs of a nimble fast paced research organization
  • Ability to work independently and as a member of a team to rapidly assess vivarium issues, questions or breaches and take appropriate action with minimal guidance
  • Ability to collect, organize, and present scientific data to the research and management teams; clearly stating interpretations and proposed next steps
  • Ability to work rigorously as an individual and passionately as part of a team
  • Extensive experience with animal models of cancer



  • Ph.D. in Cancer biology, Immunology or related field
  • Direct management experience is highly desired
  • Ability to work independently with limited oversight and as part of a team
  • Knowledge of IACUC requirements
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Federation Bio