Faculty Instructor Research - Full-Time

Research Instructor Position

Department of Pharmacology and Chemical Biology

University of Pittsburgh School of Medicine

A Research Instructor position in the Department of Pharmacology and Chemical Biology and the UPMC Hillman Cancer Center is immediately available in the laboratory of Dr. Van Houten at the University of Pittsburgh.

The funded project will focus on the interaction of DNA repair proteins at sites of damage through biochemistry, single-molecule techniques, and cell biology. The lab's current projects focus on mechanistic studies of nucleotide excision repair and base excision repair protein interactions with damaged nucleotides in DNA and chromatin. We are particularly interested in developing novel therapies and biomarkers for the treatment of cancer through monitoring or altering DNA repair capacity.

Necessary research skills include advanced molecular and cellular biology techniques. Some experience or knowledge of single-molecule techniques is desirable.

Prior experience involving the use of DNA manipulation, structure-function studies, and enzyme assays would be ideal. In addition, candidates should have outstanding critical thinking and problem-solving skills and excellent written and oral skills. Salary is commensurate with experience. Applications from women and minorities are strongly encouraged.

To apply for the position, qualified candidates with a PhD degree in genetics, biochemistry, cell biology, physiology, or pharmacology, should complete an application in the Talent Center at https://www.join.pitt.edu/#24001378.

'227742