Engineer Iii, Process Development

The Role

Moderna is working to develop first-in-class messenger RNA (mRNA) based medicines. We are seeking a highly skilled and motivated Engineer III to join Moderna's Technical Development organization in Norwood, MA.

In this role, you will support the development of manufacturing processes for Moderna's mRNA-based medicines to enable clinical and commercial supply, with a focus on process understanding and process control strategy definition, and the optimization, transfer, and characterization of manufacturing processes. The role will additionally interface with and support cross-functional teams across CMC, Research and Development, Pre-clinical and Clinical Manufacturing, Quality, and Analytical Development.

Applicants must have demonstrated experience in designing, executing, and analyzing scientific experiments. Applicants must have previous experience with chromatography, nanoparticle formulations, filtration technologies, mixing technologies, and/or statistical design of experiments. Relevant academic and/or industrial experience in drug substance or drug formulation/delivery development is expected. Applicants should enjoy working in a fast-paced, highly dynamic, and innovative environment. Collaboration through cross-functional matrix teams is required. Applicants should have exceptional time management and communications skills, with a strong attention to detail.

Here's What You'll Do

• Design, execute, and analyze experiments for existing and novel process modes

• Develop commercial manufacturing processes, characterize the process design space, and define critical process parameters

• Collect, archive, process, and organize samples for downstream analyses

• Maintain good documentation practice through electronic lab notebooks and technical reports

• Clearly communicate results to a wide audience, both internally and cross-functionally

• Execute and troubleshoot standard protocols, and develop and adapt new protocols into practice

• Maintain positive relationships with internal business partners to facilitate collaborative development across all functions

• Deliver reproducible and impactful results under ambitious timelines

• Support global site startup activities via tech transfer, process investigations and provide person-in-plant support may require domestic or international travel (up to 15% of working time).

• Additional duties as may be assigned from time to time

Here's What You'll Need (Basic Qualifications)

• BS or MS in chemical engineering, biological engineering, chemistry, biochemistry, or closely related field

• BS with 5+ years, or MS with 2+ years of relevant industry experience in bioprocess development, pharmaceutical development, or closely related area

• Hands-on experience with chromatography, ultrafiltration, normal flow filtration, and/or development of innovative unit operations or experience in nucleic acid drug development (DNA, RNA, oligonucleotides) and/or nanoparticle delivery.

• Experience in designing, executing, and analyzing scientific experiments

• Experience in laboratory work and knowledge of appropriate laboratory hygiene

Here's What You'll Bring to the Table (Preferred Qualifications)

• Excellent technical writing and verbal communication skills

• Strong interpersonal skills in dynamic settings

• Working knowledge of statistical design of experiments (DoE) and analysis of multivariate data

• Experience in technology transfer and optimization of manufacturing processes.

• Experience with analytics and biophysical characterization of nanoparticles

• Knowledge of cGMP, ICH, regulatory guidelines and QbD principles as they apply to risk management and product commercialization

• A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative.

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

• Highly competitive and inclusive medical, dental and vision coverage options

• Flexible Spending Accounts for medical expenses and dependent care expenses

• Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities

• Family care benefits, including subsidized back-up care options and on-demand tutoring

• Free premium access to fitness, nutrition, and mindfulness classes

• Exclusive preferred pricing on Peloton fitness equipment

• Adoption and family-planning benefits

• Dedicated care coordination support for our LGBTQ+ community

• Generous paid time off, including:

• Vacation, sick time and holidays

• Volunteer time to participate within your community

• Discretionary year-end shutdown

• Paid sabbatical after 5 years; every 3 years thereafter

• Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents

• 401k match and Financial Planning tools

• Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options

• Complimentary concierge service including home services research, travel booking, and entertainment requests

• Free parking or subsidized commuter passes

• Location-specific perks and extras!

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com. (EEO/AAP Employer)