Director/Senior Director, Program Team

Rubius Therapeutics, Inc. Cambridge , MA 02138

Posted 5 months ago

Rubius Therapeutics is a clinical-stage biopharmaceutical company that is generating red blood cells and engineering them into an entirely new class of allogeneic, off-the-shelf cellular medicines. Our Red Cell Therapeutics can potentially be used to replace missing enzymes for patients living with rare enzyme deficiencies, kill tumors in cancer and regulate the immune system for the treatment of autoimmune diseases. We expect to begin enrolling patients in our first clinical trial during the second quarter of 2019, which is evaluating RTX-134 for the treatment of phenylketonuria, an inherited metabolic disorder. Additionally, we plan to file our first oncology IND for RTX-240 for the treatment of solid tumors by early 2020. In total, we plan to file four to five INDs during 2019 and 2020.

We are proud of our passionate, high-performance culture one based on a set of values that are the cornerstone of who we are and how we hold ourselves accountable. Founded in 2013, we are based in Cambridge, MA and currently expanding across all functions within the organization. Having completed our initial public offering in July 2018, (Nasdaq: RUBY), we are well capitalized to execute our vision of creating life-changing cellular medicines. Red blood cells are no longer just for carrying oxygen. Check us out at www.rubiustx.com or follow us on Twitter and LinkedIn.

Summary

We are looking for a motivated, empowered and driven Program Team Director to lead the cross-functional program team in developing and executing strategic plans from pre-IND planning through BLA/MAA approval. Reporting to the VP, Program Management, the qualified individual will provide Program Management expertise for complex and/or multiple development programs and will drive program team decision making and alignment. The successful candidate should drive effective communication related to program strategy in order to ensure active management of issues/risks/opportunities related to all internal and external activities.

The Program Team Director will work closely with the Program Team Lead and with all functions/divisions for developing an integrative program development plan to support critical path/activities, identifying risks, developing contingencies, budget tracking and forecasting, resourcing planning and alternative strategies to remove barriers to ensure team success. The Program Team Director may also lead key initiatives that have cross-functional or cross-divisional impact that are critical to the business including process improvements with significant organization impact and manages, as needed, non-project responsibilities which can include process and system optimization.

Responsibilities

  • Responsible for the operational management and leadership of the assigned program. Develop and maintain with the Program Team Lead the program strategy and drive the integrated development plan in conjunction with all lifecyle management requirements

  • Proactively identify critical path activities and resource requirements to ensure successful delivery of program goals and objectives.

  • Drive clarity and alignment with relevant stakeholders to communicate risks/challenges to drive progress and ensure appropriate prioritization

  • Accountable to drive and manage program stage-gate progression through development process and oversee the appropriate transition phases from Discovery to Commercial

  • Responsible for leading preparation efforts for governance engagement to support and drive program deliverables including preparing for Portfolio Strategy Team review

  • Optimize program execution without compromise to quality to ensure highest level of operational excellence

  • Provide clarity and direction in urgent or unexpected situations. Independently resolve complex issues and competing priorities that may impact achievement of goals, creates mitigation plans and drives to resolution

  • Responsible to facilitate project/program execution from Pre-IND planning through BLA/MAA approvals utilizing project management tools and processes to maintain strategic direction, project schedule/timeline, communications, budget/cost and identify and mitigate risks.

  • Drive the Program Team meetings to ensure timely progress and proactively identify potential issues or obstacles and achieves resolution or plans contingencies. Follow issues through to resolution ensuring that all key stakeholders are informed of outcomes and program implications

  • Maintains program-related documentation such as program plans, decision logs, risk management tools, and project goals ensuring appropriate access

  • Develop and ensure accuracy of program timelines, and align with each line functions priorities and objectives

  • Foster strong relationships and support effective and impactful communications with management, team members and functional line managers in order to ensure active management of issues/risks/decisions/opportunities

  • Provided direction and mentor junior colleagues to work strategically and drive results; identifies opportunities for junior Program Managers to demonstrate their abilities, uses effective coaching techniques to refocus energy and address barriers to success and lead by example

  • May have responsibility for line management of Associate Director and/or Senior Manager level Program Managers as well as contractors within the Program Management function

Qualifications & Education

  • Advanced degree in life sciences or a relevant scientific discipline (or bachelor's degree with experience equivalent to graduate degree)

  • A strong leader with a minimum 12+ years of experience in program management in life sciences (biotechnology or pharmaceutical) managing early to late stage cross functional program teams

  • Demonstrated track record of success working on an international multidisciplinary drug development team, preferably in a complex matrix environment

  • Cell/Gene and/or Oncology therapy experience preferred

  • Significant experience in the drug development process including discovery, clinical, regulatory, CMC and commercial functions from research candidate evaluation to late stage development preferred

  • Fluent in English. Excellent written and verbal communications skills; including presentation and facilitation

  • Expert planning and tracking skills, with the ability to capture details and summarize effectively for bridging across diverse, cross-functional and multi-national teams

  • Knowledge of resource (forecast and headcount) planning and management. Well organized, focused on results, capable of managing multiple projects, excellent time management skills with respect to priorities and self-management

  • Proficiency with program/project management tools and with MS WORD, MS Project, Excel, Power Point, SharePoint. Experience with Enterprise management tools a plus

  • Ability to handle work flow in a fast paced environment

EEO Statement: Rubius Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.

Recruitment & staffing agencies: Rubius Therapeutics does not accept agency resumes unless contacted directly by internal Rubius Talent Acquisition. Please do not forward resumes to our careers@rubiustx.com account, Rubius employees or any other company location; Rubius Therapeutics is not responsible for any fees related to unsolicited resumes.


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Director/Senior Director, Program Team

Rubius Therapeutics, Inc.