Director/Senior Director, Clinical Imaging (US Based)

About Us

ARTBIO is re-defining cancer care by developing a new class of radioligand therapies (RLT) which harness the power of 212Pb and deliver it directly to the tumors. Targeted RLT is one of the fastest growing areas of oncology research and investment. The foundational technology, termed AlphaDirect, was born out of elegant research by our scientific founders, Roy Larsen and Øyvind Bruland, inventors of XofigoTM. ARTBIO is leveraging this groundbreaking science and expediting novel Drug Discovery targets which broadly exploit the unmet medical need and opportunity in revolutionizing cancer care. Supported by a committed investment board including Omega Funds, F-Prime Capital, Radforsk and Third Rock Ventures, ARTBIO has built a highly experienced, multi-disciplinary team of drug-hunters and developers. For more information on our strategy and emerging pipeline, please visit www.artbio.com and follow-us on LinkedIn.

As an emerging, global biotech with locations in Boston, Massachusetts, Basel, Switzerland, London, England and Oslo, Norway, we take advantage of diverse scientific depth and insights which makes ARTBIO a unique place to work. We are driven by a desire to do better for cancer patients, lowering the burden of toleration and safety while at the same time raising the bar on clinical efficacy and duration.

Summary

We are seeking a Senior Director of Clinical Imaging will be expected to take on a highly visible role with internal and external stakeholders through development of the strategy and management of imaging for clinical protocols in ARTBIO’s Radioligand Therapy (RLT) clinical development programs. As a critical member of the Program Team, you will work closely with program leads, functional heads and subject matter experts to advance the company’s development pipeline.

Responsibilities

• Develops clinical imaging strategies designed to support the clinical development plans for RLT agents
• Designs and implement imaging protocols, plans and procedures for clinical studies
• Provides oversight and guidance for all aspects of Medical Imaging for clinical trials.
• Delivers subject matter expertise regarding advanced imaging techniques (including  PET/CT, SPECT, MRI, CT and other modalities as needed), image evaluation, and dosimetry estimation.

• Provides scientific and technical supports/oversite in research activities.
• Manages the resolution of technical/radiological/dosimetry questions and issues on a study and program level.
• Leads imaging/dosimetry academic collaborations, contractors, vendor/partner interactions.
• Oversees CRO vendors including imaging core labs and dosimetry vendors to ensure they optimally execute clinical imaging projects
• As a member of the oncology clinical team, ensures strong collaboration between functions, collaborators, and vendors and high team performance.
• Participates in program development/enhancement, financial planning and analysis, metric and reporting, shared services relationship management, contract compliance, and process improvement.

Qualifications & Education

• At least 12 years of industry experience; advanced degree required, Ph.D. preferred, in Medical Physics or Radiation Protection

• Demonstrate a strong technical understanding of and commitment to medical imaging and dosimetry in the field of RLT development

• Experience of Medical Imaging, Regulatory and Clinical Research processes

• Direct experience designing and managing imaging aspects of clinical protocols for oncology RLT agents (including study design, endpoint selection, dosimetry, harmonization between clinical sites, imaging core lab oversight, etc.)
• Specific experience with imaging study design and direct/indirect estimation of normal organ and tumour dosimetry for early-stage clinical development in RLT agents
• Interpersonal skills, organization and communication skills, leadership skills and problem-solving competency
• Demonstrated ability to work well under pressure
• Strong organizational, planning, and time management skills
• Demonstrated ability to work well with team members and independently
• Commitment to continuous learning and staying updated on industry trends and advancement