Director, Protein Sciences

The Role: BigHat Biosciences is seeking an exceptional, people-focused Protein Sciences leader to scale BigHat's Protein Sciences team, capabilities, and impact. This role will grow a talented team of protein scientists and set an ambitious technical roadmap in the mission of advancing BigHat's state-of-the-art antibody engineering platform and therapeutic pipeline. The Role: BigHat Biosciences is seeking an exceptional, people-focused Protein Sciences leader to scale BigHat's Protein Sciences team, capabilities, and impact. This role will grow a talented team of protein scientists and set an ambitious technical roadmap in the mission of advancing BigHat's state-of-the-art antibody engineering platform and therapeutic pipeline.

Key Responsibilities

• Setting and executing a vision for how Protein Sciences can advance BigHat's platform and therapeutic pipeline including developing a roadmap for the full suite of protein sciences activities, including protein production, purification and characterization capabilities that broadly serve the Science and Development organizations

• Deeply understanding the needs of Platform and Programs teams in order to architect and prioritize Protein Sciences activities company-wide

• Growing a high performance team emphasizing individual development of talented scientists and supporting company-wide cross-functional interactions

• Ensure programs needs are met for producing, purifying and characterizing antibodies from screening through candidate declaration

• Drive continuous process improvements to enable higher throughput, yield, purity, quality of protein products and to improve efficiency and data-richness of related lab processes

• Collaborate closely with Engineering, Product, Data Science and Automation team members to ensure BigHat's technical ecosystem fully supports Protein Sciences needs

• Collaborate closely with BigHat executives, AI/ML, and other team members to ensure a tight linkage between the experimental and machine learning platform components.

• Collaborate closely with Translational Research and Development teams to ensure clinical candidates are robustly characterized and meet high standards of developability

Skills Knowledge and Expertise

You have a stellar track record at top-tier institutions or companies; a strong scientific background (Ph.D.) and publication record; 10+ years of pharma/biotech industry experience in protein biochemistry including protein expression, purification, and assessment of protein biophysical properties; demonstrated hands-on experience in the discovery and development of next-generation biologics; excellent communication skills; experienced at building and leading high-performance scientific teams, experience working with computational and software teams, thrive in a fast-paced environment helping to launch, operate and grow a high-potential startup. If you love tinkering, optimizing, and diving headfirst into diverse, highly technical projects BigHat could be the right home for you.