Bioinformatics Scientist/Senior Bioinformatics Scientist - Cancer Biology/Genomics

Bluestar Genomics San Francisco , CA 94107

Posted 1 week ago

Use your skills in the application of computational methods and development of novel algorithms toward the design of novel molecular diagnostic signatures in the treatment of cancer and other disorders. You will develop novel analytic methods and computational pipelines for the analysis of epigenetically derived nucleic acid sequence data from patient samples. The analytic methods will be employed to answer specific clinical questions that contribute to the care of disease through the design and implementation of novel molecular diagnostic assays.

You are familiar with leading edge genomics technology platforms, inclusive of next generation sequencing, and have proven experience in the direct development of new bioinformatics methods and production pipelines for clinical studies. You have the necessary technical skills to analyze genomic data from large scale clinical data to enable the discovery of statistical association, error measurement and feature detection.


  • Analysis of genomic data from clinical studies to enable feature detection. A comprehensive understand of genome alignment issues and sequence error detection and modelling.
  • Generation of statistical models that cover data representation and building of simple and complex classifiers for diagnostics score development.
  • Building prototype pipelines to enable large scale data analysis and ultimately production level pipelines.
  • Evaluating and supporting software tools for sequencing, statistical and data analysis.
  • Ability to present results clearly and concisely to cross-disciplinary audiences
  • Communicating hypotheses, data and experimental design to colleagues, collaborators, and advisors.
  • Exemplify our core values - Visionary; pioneering; truth seeking; driven; honest and considerate communication; embraces diversity - and operate with transparency and integrity.


  • PhD in Genetics, Genomics, Biochemistry and Molecular Biology or related discipline and at least 3+ years of work experience, or a Bachelor/Masters Degree (Biological discipline) with 10 years of work experience.
  • Excellent interpersonal, written and spoken communication skills. Mentor junior members of the team.
  • Established record of publication of genomic and genetic studies in leading peer-reviewed journals.
  • Programming languages (Python, Java and R), pipeline development and workflow management systems.
  • Network and cloud-based Unix/Linux environments to enable the development of production ready remote computational pipelines. Inclusive of but not limited to AWS, Docker and Kubernetes.
  • Familiarity with studies and datasets found in public domain databases at NCBI, TCGA and SRA
  • Familiarity with a variety of machine learning techniques is desirable
  • Preferred: Relational database experience with strong SQL skills


Come join us in addressing large healthcare needs through precision epigenomic medicine!

Founded out of the Stanford laboratory of Steve Quake, Bluestar Genomics is reinventing non-invasive diagnostic testing using epigenomic technologies and next generation sequencing. Our liquid biopsy technologies provide the earliest possible measure of cancer biology without biopsy, enabling improved clinical and health system outcomes through simple and convenient blood testing. We are passionate and dedicated to discovering and developing clinical applications that will make significant differences in cancer and other large healthcare needs.

We are passionate and dedicated to discovering and developing medicines that will make a significant difference in cancer and other epigenomic-driven diseases. Our technologies provide novel insight and quantitation of human health and disease, with our focus on precision medicine applications improving both clinical and health system outcomes.

We provide generous benefits to all employees, including stock options and a fully-stocked kitchen! We value your physical presence in our office in building our cohesive team. We look for extraordinary lifelong learners with a passion and growth mindset for these areas, and for combining biological ingenuity with AI and data analysis. Led by a team with extensive experience bringing products from concept to market, we are an equal opportunity employer and value diversity at our company. We are building a world-class company, based in San Francisco and San Diego.

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Bioinformatics Scientist/Senior Bioinformatics Scientist - Cancer Biology/Genomics

Bluestar Genomics