Astrazeneca - UVA Postdoctoral Research Associate - Cardiovascular Functional Genomics

The Miller Laboratory at the University of Virginia seeks a talented postdoctoral research associate with a background in a life sciences field to apply systems genomics approaches to investigate mechanisms of inherited cardiomyopathies. Available projects include the generation and computational analysis of single-nucleus (e.g., snATAC/snRNA-seq), and spatial (e.g., spatial transcriptomics, proteomics) omics datasets from healthy and diseased subjects of ancestrally diverse backgrounds.

The candidate will also contribute to functional genomic screens to validate discoveries in vitro and in vivo. The overall goals of this work are to contextualize rare and common genetic variation associated with cardiovascular diseases to inform early-stage detection and prevention. There will also be opportunities to classify common disease subtypes using machine learning approaches and identify clinically relevant targets/biomarkers for myocardial diseases.

This unique position is funded for 3 years through a partnership with AstraZeneca (Gaithersburg, MD), where the candidate will be exposed to a dynamic cross-functional training environment. At UVA the candidate will have access to a broad range of population genetic and genomic datasets through large-scale consortia projects, high performance computing resources, and will be exposed to a stimulating, multi-disciplinary and inclusive environment in the Center for Public Health Genomics (CPHG). This work will involve close collaborations with AstraZeneca scientists to broaden training in both data science and translational cardiovascular fields.

Minimum Requirements:

Candidates must have a PhD in a life sciences or quantitative field (required in hand by appointment start date).

Preferred Qualifications:

Experience in statistics or genetics is desired, including proficiency in R, python (or other scripting languages). The successful candidate will also have a strong working knowledge of biomedical fields such as human genetics, molecular/cell biology, physiology etc. Excellent written and verbal communication skills are required, as is the ability to work in a cross-functional team.

As part of the AZ-UVA postdoc mentoring program, the candidate will be encouraged to generate impactful publications, present in national and international scientific meetings, as well as participate in AZ networking and career development events.

To learn more about the position and the research please contact Dr. Clint Miller, clintm@virginia.edu

This is a 12-month appointment with the possibility of renewal contingent upon satisfactory performance and the availability of funding. Salary is commensurate with education and experience.

This is an Exempt level, benefited position. For more information on the benefits available to postdoctoral associates at UVA, visit postdoc.virginia.edu and hr.virginia.edu/benefits .

This position will sponsor applicants for work visa who meet the qualifications.

This position will remain open until filled. The University will perform background checks on all new hires prior to employment. A completed pre-employment health screen is required for this position prior to employment.

Physical Demands:

This position can spend extensive periods of time standing and squatting while conducting experiments or caring for animals. Also requires keyboarding and other bench work and animal procedures requiring finer finger manipulation.

The University of Virginia is an equal opportunity/affirmative action employer. Women, minorities, veterans, and persons with disabilities are strongly encouraged to apply.

To Apply:

Please apply through Workday , and search for R0048824. Internal applicants must apply through their UVA Workday profile by searching 'Find Jobs'. Complete an application online with the following documents:

• CV

• Cover letter

• Contact information for 3 references

Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission. Applications that do not contain all required documents will not receive full consideration.

For questions about the application process, please contact Yelena Markazyan, Academic Recruiter, ym3mm @virginia.edu .

This position is located in Charlottesville, VA. For more information about UVA and the Charlottesville community please see http://www.virginia.edu/life/charlottesville and https://embarkcva.com/

The University of Virginia, i ncluding the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician's Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences.

We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.