Associate Scientist / Scientist Data Science, Oncology Biomarker Development

Genentech South San Francisco , CA 94080

Posted 4 days ago

We seek a highly motivated Associate Scientist / Scientist within Oncology Biomarker Development (OBD) Data Science to support biomarker and diagnostic development efforts focusing on Genentech's cancer immunotherapy pipeline. The incumbent will apply advanced bioinformatics and data analytics in collaboration with a group of translational biomarker scientists to execute on biomarker and companion diagnostic strategies for programs in clinical development. The incumbent will also apply these methods to characterize mechanisms of response and resistance to immunotherapy and inform novel research activities.

For this particular position, a strong background in cancer biology, immunology, bioinformatics and/or biostatistics, evidenced by peer reviewed publications in top tier journals, will be an important asset. The successful candidate is expected to effectively interact with cross functional teams; analyze multidimensional data supporting innovative clinical development programs and publications focused on biomarkers and disease mechanisms; interact with key internal and external collaborators and investigators; and promote collaborative efforts to advance biomarker research.

As an Associate Scientist / Scientist, you are expected to:

  • Manage and support analyses of multidimensional early- and late-stage clinical biomarker datasets including NGS-based DNA and RNA profiling

  • Effectively manage internal and external scientific collaborations

  • Drive scientific and technical innovation collaboratively with other members of the department

  • Support development and execution of exploratory biomarker and companion diagnostic strategies for multiple projects

  • Support publications in high impact scientific, technical or medical journals

  • Represent the biomarker team externally through interactions with our key investigators and public presentations

  • Participate and thrive in a fast-paced, interactive and team-oriented culture

Who You Are

  • PhD degree in a relevant scientific field (e.g., immunology, molecular biology, cancer biology, genomics, or bioinformatics)

  • Minimum of 2 years postdoctoral experience in basic or translational research either in an academic or industry setting

  • Strong bioinformatics programming skills using R/Bioconductor and/or Python

  • Experience analyzing and interpreting high throughput genomic data, especially RNA-seq, whole exome sequencing and targeted NGS, is highly desired

  • Experience in integrating multiple omics layers in association with clinical and laboratory parameters would be highly beneficial

  • Experience with modern machine learning methods is desired

  • Experience in clinical drug development is beneficial, including understanding of critical development functions, such as biomarker development, operations, and biostatistics

  • Demonstrated record of scientific leadership as evidenced by first or senior author publications in high impact journals

  • Outstanding presentation and communication skills

#DevSci

#LI-BJ1

Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genomic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer and other serious illnesses. Please take this opportunity to learn about Genentech, where we believe that our employees are our most important asset and are dedicated to remaining a great place to work.

Genentech is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.


icon no score

See how you match
to the job

Find your dream job anywhere
with the LiveCareer app.
Mobile App Icon
Download the
LiveCareer app and find
your dream job anywhere
App Store Icon Google Play Icon
lc_ad

Boost your job search productivity with our
free Chrome Extension!

lc_apply_tool GET EXTENSION

Similar Jobs

Want to see jobs matched to your resume? Upload One Now! Remove
Senior Scientist Oncology And Inflammation Biomarker Discovery

Amgen Inc.

Posted 1 week ago

VIEW JOBS 1/12/2020 12:00:00 AM 2020-04-11T00:00 Career Category Research Job Description Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is developing a Biomarker-Discovery group to support therapeutic programs. The Amgen Inflammation & Oncology Research Group is looking for a Scientist dedicated to biomarker discovery in the areas of immuno-oncology and inflammation. In this role you will work cross-functionally and interact closely with both the clinical biomarker and discovery research groups. The position will focus on the discovery of biomarkers to support the progression of therapeutic candidates from discovery to early clinical development. The role is responsible for: Developing deep disease area expertise for key indications in the therapeutic area's strategy Discovery and prioritization of disease stratification and target engagement biomarker candidates relevant to the pipeline Developing, implementing, and executing a therapeutic biomarker discovery strategy across several programs Generating and transitioning key pharmacodynamic and patient stratification/selection biomarker discovery data in support of clinical biomarker assay and companion diagnostic test development Supporting translational biomarker activities for therapeutic assets including investigator meetings/ad boards and investigator sponsored studies for correlative biomarker research together with the Clinical Biomarker lead The role is expected to work in a highly matrixed environment to drive scientific and technical innovation collaboratively with other members of the Inflammation & Oncology group, as well as with other functions including the Clinical Biomarker & Diagnostics Team, Translational Medicine, Therapeutic Discovery, Human Genetics and Computational Biology. Basic Qualifications Doctorate degree and 2 years of scientific experience OR Master's degree and 5 years of scientific experience OR Bachelor's degree and 7 years scientific experience Preferred Qualifications PhD or MD, with postdoctoral training and research experience in the fields of immunology, oncology and/or cancer immunotherapy Demonstrated track record of independent critical thinking and scientific achievement in the areas of immunology and/or oncology as demonstrated by multiple high impact publications Demonstrated experience in leading independent research and drug development Experience with implementing multiple technology platforms Experience with computational biology Strong verbal and written communication skills. Ability to collaborate and troubleshoot to solve problems Experience working in teams and consistently delivering results At Amgen, our mission is serving patients. Our staff are dedicated to pushing the boundaries of science to transform medicine and turn the tide on serious illnesses. Central to achieving this mission is our "people-first" philosophy. We recruit the best talent, build an environment that facilitates career growth, and provide staff with the opportunity to make significant contributions for patients and our business. Consistent with our core leadership value of "Develops the Best Team," we are seeking leaders that prioritize the development of talent. As a manager, your first priority and primary role is to accelerate the performance and development of your team. We expect managers to exemplify strong leadership and champion self-awareness and career development. Ways that you will display your leadership acumen in this role include: * Mentoring, coaching, and developing staff to build highly-skilled, diverse, and inclusive teams * Fostering a positive and respectful work environment that encourages staff retention and motivates individuals to work toward common goals and priorities * Ensuring that staff understand how their efforts and contributions make a meaningful impact to the business * Growing core skills and capabilities among staff, particularly in learning agility, problem solving, strategic and creative thinking, flexibility, resilience, effective communication, prioritization, delivery of results, and continuous improvement * Making accurate evaluations of your team's skills and competencies and providing timely and respectful feedback, including direct delivery of difficult messages * Developing an understanding of your team's career objectives and serve as a thought-partner in their career development plans A Fortune 150 company operating in nearly 100 countries around the world, we invest in highly skilled, dedicated and collaborative individuals who are ready to contribute to our mission in meaningful ways and make a difference in the lives of our patients. That's why, as a member of our cross functional, cross discipline team, we provide you with valuable opportunities to broaden your experience and maximize your potential. Focused on the industry's most compelling scientific discoveries and housed within industry leading facilities within the heart of the world's leading biotechnology hub, our colleagues are growing our pipeline through groundbreaking innovations. We believe in rewarding those who do rewarding work and are committed to providing careers that can help turn the tide of serious, life interrupting illnesses. Join Us If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance. Amgen Inc. South San Francisco CA

Associate Scientist / Scientist Data Science, Oncology Biomarker Development

Genentech