Associate Scientist Iii, Biology (Hemoglobinopathies)

Position: Associate Scientist III, Biology (Hemoglobinopathies) Location: Boston, MA

Job Id: R089-R # of Openings: 1

We seek an energetic and motivated Associate Scientist III to join our Biology team. In this role you will help develop novel viral-based genomic medicine for hemoglobinopathies and other hematological disorders and work collaboratively with our Biology team. You will conduct experiments that functionally evaluate hematopoietic stem cells (HSCs) and lineages in vitro and ex-vivo.

This position offers a unique opportunity to be a vital member of a team dedicated to moving a novel genomic medicine drug candidate into the clinic. Join us and be part of building a company revolutionizing the reach and access of the curative power of genomic medicines for patients with serious diseases.

Responsibilities:

• Perform primary cell isolation and culture

• Conduct and execute complex in vitro and ex vivo cell-based assays

• Contribute to complex in vivo studies, assisting with mouse handling, dosing, necropsy, and downstream tissue processing

• Analyze data and present results at group meetings and conferences

• Contribute to publications and written reports for regulatory filings

• Maintain laboratory equipment and rooms as required

• Other duties and responsibilities as assigned

Qualifications:

Required:

• A Bachelor's Degree in a biological science with a minimum of three years or a Master's Degree with a minimum of two years of post-graduate academic and/or industry experience

• Demonstrated in vitro experience to study HSC and/or immune cell biology

• Ability to design experiments and troubleshoot technical hurdles independently

• Rodent handling, dosing (IV, IP, IM, SC) and tissue collection, particularly of hemato-lymphoid organs (bone marrow, spleen, blood)

Preferred:

• Proficiency with multi-color flow cytometry

• Additional in vivo skills: retro-orbital dosing, tail vein injections, blood collection by cardiac puncture

About Ensoma:

Ensoma is a place where you can ask the big questions. We look at gene therapy today and ask: What if we could eliminate the patient burden? What if we could treat diseases that affect millions? What if we could treat people anywhere around the world?

Ensoma was founded to answer these questions through our Engenious platform that can transform the hematopoietic (blood & immune) system with a single treatment. Our Engenious gene therapy platform is the first to precisely engineer any or all hematopoietic and immune cells with a one-time, off-the-shelf in vivo treatment. Engenious therapies have an unmatched capacity to deliver all modern genetic modification tools and set a new standard for versatile cell programming and control across a range of complex diseases. We believe the future of medicine lies within us - and this bigger, bolder vision for gene therapy needs incredible people to make it a reality.

For our team, realizing this vision is personal. Founded and guided by leaders drawn from the top of the cell and gene therapy field, we feel an urgency and passion for our work driven by its potential global impact.

A meeting at Ensoma is a space where curiosity, trust, authenticity, problem-solving and professional development are celebrated. A career at Ensoma is an opportunity to be part of the team building the future of medicine.

Ensoma is a 5AM Portfolio company supported by top-tier investors, strategic partners, and a passionate team committed to a bold global vision for genomic medicines. Ensoma is headquartered in Boston, Massachusetts and has operations in Copenhagen, Demark. For more information, please visit www.ensoma.com.