MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies. Our team of 300+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer as well as various autoimmune disorders and infectious diseases. Our products and platforms have attracted multiple partnerships with leading pharmaceutical companies around the globe.
The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization.
Summary of Position
The Associate Scientist I is responsible for characterizing biologic drug candidates by performing in vitro cell-based bioassays/experiments in the fields of immunology, cell biology and oncology. This individual is also responsible for analyzing data, providing interpretations, recommendations and conclusions in a timely and accurate manner. This position works closely with other functional groups to provide technical support for processing and analyzing patient blood samples from early phase clinical immunotherapy trials.
Responsibilities and Job Duties
Designs and executes in vitro immune cell-based experiments within given key parameters/instructions while ensuring data quality and timely execution
Seeks to understand the broad objectives of the project as well as the individual role in achieving those objectives, and modifies experimental plan when required
Analyzes research data accurately and interprets research results to answer scientific questions
Writes assay protocols and experimental procedures incorporating scientific rationale and necessary technical information for assay development
Operates laboratory instruments including a flow cytometer, fluorescent plate reader and cell sorter. Responsible for ensuring the instruments are properly maintained and for notifying the appropriate service providers to provide regular maintenance and/or repair the equipment in a timely manner
Learns, understands and masters new experimental techniques required for research
Processes human blood samples to support clinical immunotherapy trials
Education & Experience
Bachelor's degree in Cell Biology, Immunology or Molecular Biology or related discipline and a minimum of 5 years of directly related experience; or Master's degree in immunology, cell biology or related discipline with 2 years of directly related experience
Recent experience with isolation of human PBMCs and purification of major lymphocyte populations from human peripheral blood, flow cytometer-based immunophenotyping, lymphocyte proliferation assays, ELISAs, and culture of human lymphocytes.
Knowledge, Skills and Abilities
Strong knowledge of various analytical methodologies including but not limited to: flow cytometry and ELISA
Excellent mammalian cell or cell line culture skills
Knowledge of human and rodent immune cell biofunctions
Excellent record keeping, organizational, written and verbal communication skills
Ability to set up assays and conduct technical troubleshooting analysis
Ability to analyze data and provide a critical interpretation of results
Works collaboratively with other members of the team and research groups
Ability to handle multiple priorities in a fast-paced environment
Strong interpersonal skills for interfacing with other functional groups
Prior work experience in biotechnology and/or pharmaceutical companies
MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email firstname.lastname@example.org or call (301) 354-3566 and/or 711 for TTD/TTY service.
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