How will you make an impact?
As an Associate in the Analytical Sciences (AS) Laboratory, you will support the development, qualification and execution of cell-based, nucleic acid-based, protein-based and chemistry-based assays that support quality control of cell and gene therapy products under development and manufacturing.
What will you do?
Support development, validation and execution of a variety of analytical methods including, but not limited to, real time PCR (vg titer, residual DNA), digital droplet PCR, ELISA (capsid titer and residual protein), plaque assay, TCID50 (infectious titer), replication competent virus assay, agarose gel electrophoresis, SDS-PAGE, immunoblotting, immunocytochemistry, infectivity, etc. (>80% of the time)
Maintain cell lines and lab equipment in the Analytical Sciences lab, share responsibility for lab management duties
Independently execute analytical assays in alignment with AS project needs
Analyze data (including statistical analysis), present results and conclusions to the team
Assess existing methods/processes and identify areas for further innovation and improvements (improved sensitivity, reduced turnaround time etc.)
May be required to work on a different shift (afternoon or weekend shift)
Other duties as assigned; travel as needed
Keep current on Environment, Health & Safety policies.
How will you get here?
Broad technical proficiency, ability to solve complex issues independently
Significant laboratory documentation experience
Familiar with GLP requirements; some knowledge of cGMP requirements of biopharmaceutical manufacturing
Knowledge, Skills, Abilities
Knowledge of analytical assay principles and procedures, and related instrumentation
Knowledge of cell and gene therapy vector production desirable.
Ability to work both independently and as part of a team.
Strong interpersonal and communication skills, verbal and written
Some travel is required (10-20%)
Ability to function in a rapidly changing environment & handle multiple priorities.
A flexible work schedule is required.
Ability to lift up to 25 lbs.
Thermo Fisher Scientific Inc.