Associate Engineer, Formulation Sciences

The Position

We are seeking an Associate Engineer to join our Formulation Sciences team focused on lipid nanoparticle (LNP) discovery and development for Verve's novel CRISPR-based gene editing therapies. The successful candidate will be responsible for LNP process development, scale-up, and characterization working as part of a multidisciplinary fast-paced team environment. The ideal candidate will have process development industry experience with a desire to contribute to a team focused on championing nanomedicinal products and developing manufacturing solutions based on strong scientific principles.

Job Responsibilities

• Design, prepare, and characterize lipid nanoparticles (LNPs) for screening critical process parameters (CPPs) and critical material attributes (CMAs) that impact critical quality attributes (CQAs)

• Design and execute a wide range of experiments including DoEs to advance LNP technology and process development

• Participate in defining the technical requirements for process implementation at a CMO, including equipment specification/selection, draft procedures and recommended operating parameters/ranges

• Write protocols, perform experiments, organize and analyze data, interpret results, record experiments in an electronic lab notebook, and summarize work in presentations and technical reports

• Assist in ordering supplies, making reagents, and maintaining a safe and high-performing laboratory

• Multi-task across several projects and manage time effectively to achieve results

• Collaborate with multiple cross-functional teams

• Other duties as assigned

Qualifications

• Bachelor's degree in chemical engineering, bioengineering, chemistry, pharmaceutical sciences, or another related field or an Associate's degree in a related field with 2+ years of relevant industry experience.

• Experience with lipid nanoparticle formulations and analytical characterization methods preferred

• Strong problem-solving skills, and creative/innovative approach in problem solving

• Ability to work independently and in very dynamic interdisciplinary team environments. Proven record in working with partners/collaborators is desirable

• Organized, detail-oriented, and innovative self-starter who continuously seeks to improve existing laboratory methods and processes

• Effective verbal and written communication skills; proficiency in literature search and relevant computer software skills are required

• Knowledge of practices and equipment used to run manufacturing processes in a GMP environment, including TFF, sterile filtration, single-use technology, and sterile/aseptic processing preferred