Associate Director Clinical Pharmacologist

Astrazeneca PLC Gaithersburg , MD 20877

Posted 3 days ago

Do you have great experience and expertise in clinical pharmacology, PK, PKPD, Model Informed Drug Development and its application in drug development? Would you like to apply this expertise in a company that is following the science and turn ideas into life changing medicines? If yes, we have the position for you at AstraZeneca!

This is an opportunity for a hardworking and engaged individual to join our growing Clinical Pharmacology and Quantitative Pharmacology team at AstraZeneca in Gaithersburg, MD, US as an Associate Director Clinical Pharmacologist supporting large and small molecule projects across full development within the therapy area of Respiratory & Immunology.

Within the Clinical Pharmacology and Safety Sciences function, we have a state-of-the-art quantitative clinical pharmacology group with a diverse and uniquely skilled team of clinical pharmacometricians and clinical pharmacology scientists. Gaithersburg is a key research and development location for our Respiratory & Immunology area.

There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

What you will do:

You will work closely with clinical pharmacometricians, physicians and other scientists, and apply your expertise and leadership skills to contribute to the strategy of the clinical program and the design and interpretation of clinical studies. You will influence key decisions in early and late phases of clinical development.

In collaboration with clinical pharmacometricians, you will represent Clinical Pharmacology and Quantitative Pharmacology in cross-functional project teams, and take responsibility for developing the clinical pharmacology strategy.

The work includes integration of relevant data, such as dose information, pharmacokinetics, biomarkers and clinical endpoints within and across studies, compounds and development stages. You will take part in identifying opportunities to apply model informed drug development to accelerate and inform decision making. You will communicate your findings within and outside of AstraZeneca and publish in peer reviewed journals.

Essential in the role:

  • PhD or equivalent (M.Sc/Pharm.D.) level expertise in a relevant field.

  • 3 years + industry experience or equivalent in pharmacokinetics and clinical pharmacology aspects of drug development

  • Experience of writing and reviewing clinical trial protocols and reports and regulatory documents such as INDs, IBs, NDAs or BLAs.

  • Knowledge of pharmacokinetics, its clinical application and regulatory context.

  • Knowledge and experience in use of PK and PKPD modeling applied to life sciences.

  • Biological understanding of disease and drug action.

Desirable in the role:

  • Track record in creating and delivering on clinical pharmacology strategies of both small and large molecules.

  • Recognised clinical pharmacology expertise demonstrated by scientific publishing in the field of clinical pharmacology.

  • Early and late phase clinical development experience.

We truly believe that everyone contributes with a unique set of competence. Your passion for personal development combined with support from colleagues, mentors and leaders, will ensure you maximise your skills, abilities and contribution. You have a real passion for Clinical Pharmacology, along with a collaborative nature and ability to work in multi-disciplinary global teams.

Why AstraZeneca?

Our workforce reflects the people we serve - diversity is embedded in everything we do. We're at our best and most creative when drawing on our different views, experiences and strengths.

Thrive in an energising environment where challenging work goes hand in hand with development. With opportunities, recognition and bright minds, there's no better place to unlock learning and build a long-term career.

Does this sound like your next challenge? Apply today!

Additional information:

https://www.astrazeneca.com/

AstraZeneca has taken critical steps to protecting colleagues, loved ones, and patients from COVID-19 and its variants. COVID-19 vaccination is required for all US employees, and weekly PCR COVID-19 testing is required for those who are unvaccinated or have an approved accommodation.

Date Posted

03-Jan-2022

Closing Date

27-Mar-2022

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.

We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.



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