Associate Director, Biotherapeutic Engineering

About the Role

Position is onsite in Cambridge, MA

#LI-Onsite

We are seeking a highly motivated scientist and leader specialized in engineering biologics to join the Biotherapeutic Engineering and Bioconjugation (BEC) group within BRC in Cambridge, Massachusetts as an Associate Director Biotherapeutic Engineering. The BEC group drives a diverse portfolio of pipeline programs and innovation for bioconjugations, therapeutic proteins, multifunctional antibodies and beyond. Through innovative and rational protein design the BEC group works collaboratively with Disease area groups to broaden the use of biologics into therapeutic applications where conventional antibodies have limitations.

As an Associate Director of Biotherapeutic Engineering, you will have an opportunity to join the Biologics Research Center (BRC) as a leader at the cutting edge of innovative medicine development to improve patient lives.

BRC builds the biologics pipeline in collaboration with Novartis Biomedical Research (NBR) Disease Areas and Platforms via a breadth of technologies for discovery of antibody, protein, gene therapy and RNA-based therapeutics.

Your Key Responsibilities:

• Lead a team of 10 highly talented scientists on the Cambridge site responsible to drive recombinant therapies to patients.

• Establishes mid- and long-term goals, plan of action and implementation for the local BEC team (e.g. annual objectives) in line with BRC and NBR strategy and objectives.

• Develops and implements strategy for next generation recombinant biologics for NBR.

• Represents BEC as BEC Site Head for the Cambridge site including managing the budget of the BEC unit in collaboration with global counterparts in order to meet NBC targets.

• Ensures allocation of group resources according to portfolio and platform priorities.

• Sets strategy, implements and manages outsourcing for the local BEC team.

• Collaborate with downstream development colleagues to bring lead candidates towards full development.

• Collaborates and coordinates activities with other global BRC and NBR units.

• Offer innovative approaches to scientific questions and troubleshooting efforts.

• Identifies Disease Area's unmet needs and collaborate for a novel therapeutic solution.

Diversity & Inclusion / EEO

We are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please let us know the nature of your request, your contact information and the job requisition number in your message:

• Novartis: e-mail [email protected] or call +1 (877)395-2339

• Sandoz: e-mail [email protected] or call: +1-609-422-4098

Role Requirements

• PhD with more than 10 years relevant experience and recognized both internally and externally as expert in protein engineering

• Prior experience with computational protein design/modelling and structure analysis as well as library-based approaches to attenuate functional and developability properties of protein therapeutics

• A proven track record of success as judged by publications and patents

• Demonstrated ability to recruit, retains and develops diverse, and agile associates with different expertise, seniority and tasks to ensure long term talent development and talent pipeline including succession planning.

• Background in leading and mentoring a research group consisting of associates of all levels and acting as a manager of mangers.

• Knowledge in the application of recombinant biologics to biology in the areas of oncology, immunology, neuroscience, cardiovascular and renal metabolic diseases

• Highly collaborative spirit inside and outside of department to advance programs to clinic; good communication skills, creativity, and multi-tasking in a fast-paced environment

• Excellent, oral and written communication skills, track record in scientific collaboration with a strong interest/potential in expanding beyond core science

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining

to achieve breakthroughs that change patients' lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

Benefits and Rewards: Read our handbook to learn about all the ways we'll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $151,200 - $226,800/year; however, while salary ranges are effective from 1/1/23 through 12/31/23, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

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Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together?